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 Both men and women tend to lose hair due to some hormonal changes in the body. It is mainly the alterations in the metabolism of androgen in the body that brings about hair loss. Androgen is the male hormone that plays a very important role in both hair loss and hair growth. This metabolism of androgen gets involved with an enzyme, the 5 alpha reductase which tends to combine with the male hormone, testosterone to give DHT (Dihydrotestosterone). This DHT is the natural metabolite of the human body that is the main reason for hair loss.
The most important structure of a hair follicle is the dermal papilla, which is responsible for hair growth. The cell of this dermal papilla divides and differentiates to form a new hair follicle. As this dermal papilla lies in direct contact with blood capillaries of the skin, it is responsible for deriving nutrients for hair follicle growth. This dermal papilla has many receptors for androgens; where men have more androgenic receptors here than women. |
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